I remember reading in a preview that it was possible. Does the game natively support it, or will I have to rely on my own software? Anybody know? Thanks!

Apolyton had a pic of it in one of its previews. Believe MarkG over there tried it, maybe he can tell you.

http://civilization4.net/3/171/304/

http://apolyton.net/forums/showthread.php?s=&threadid=140148&highlight=dual

Good luck!

No one ever commented on this as to whether dual monitor is possible. I am on a Matrox G400 Millenium (running very slow with the black terrain bug) and the game automatically switches to single monitor on start. If the bugs get worked out and I can eventually play it, I would love to see it on dual screen.