First impression is between "mixed" and "meh". Reminds me an aweful lot of CIV5 vanilla: Some good ideas, but mechanical problems, questionable design decisions and TERRIBLE balance. It's an okay-ish CIV5 spinoff, but not nearly as good as I have hoped.
I really hope that they will reduce the number of trade routes (or add an automation) function, because I have spend more time with re-assigning them than anything else. They are a giant PITA and by far the worst thing about the game. Not to mention they force REXing and completely flip the balance from buildings and tile improvements during the early and mid game. Blech.
The AI is also terrible. Hutama has created a carpet of doom near my station but refuses to attack, sitting there for 50 turns now. Not even his ranged units are firing. I assume it is due to a station and a lake that block some tiles - he just can't handle it.
What surprised me is how good Knowledge is. Considering that health is irrelevant I pick Knowledge first and can get the penalty reducing virtues by the time I settle my first city. The +2 science from academies is also quite strong - a 5 science tile is a powerful mid to late game option!
What I really hate is that the aliens and the alien planet have no impact past the early game. There is absolutely no feeling of colonizing a new world once you have reached turn 100+. Aliens are passive, they can easily be repelled with Ultrasonic Fences and Trade Routes become immune to them rather quickly.