I'd recommend everyone deactivate ALL THEIR MODS until compatibility of them has been ensured. I am 99% sure this is the root cause for most of the stability issues people are having.
Mods can have issue with the new patch, as usual, but corrupted graphics and the other bugs reported here are for the most part absolutely not mod related.
Still it's a good idea to make the first game after a new patch without any mod, yes, and one should always try to reproduce a bug with all mods deactivated before reporting it.