Hmm, well, I'm naturally excluding Financial leaders (so I suppose this technically isn't the
best combo...) I can't get enough of Asoka of India:
Spiritual: Simple enough, fast switching from Build-mode to War-mode, and faster happiness from temples.
Organised: Simple enough again, saving of cash behind-the-scenes allows for peaceful expansion until courthouses come along, at which point you start making loads of money. And late game cheap factories are another speed-boost, meaning you only have to take a couple of turns out of your war production for this great hammer boost. Cheap lighthouses as well.
UU (Fast Worker replaces Worker, +1
): I don't think they get any better than this. Never obsolete, can walk onto a hill or forest etc and begin work on the same turn, and moves faster. Invaluable for the first unit your capital produces, and generally provides rapid (getting the picture yet? Rapid! Rapid!) acceleration of your infrastructure.
UB (Mausoleum replaces Jail, +2
): An awesome building. At this point in the game I am well into my imperialist expansion and the bonus happiness (as well as the war weariness reduction) allows the war to continue indefinitely.
Mysticism: Grab Hinduism ASAP, and (optionally) cottage up your capital. Provides an excellent gold producing powerhouse.
Mining: Not bad, gives your initial Fast Worker something to do if you've got hills, and by the time he is out you could have gone straight for Bronze Working, which will give him plenty to do while you research other useful worker techs.
I tend to play Asoka whenever I go up a level in difficulty. The strategy is typically go for Hinduism; rapidly claim as much land as possible, peacefully if you can, and develop it at lightning speed with Fast Workers; normally kick off the war machine in the medieval period or as soon as my courthouses are up and running. Steamroll a civ and rapidly develop the land in your image using Fast Workers, and you are ready to move on to the next opponent. Keep the war up and if angry citizens are a problem go for Mausoleums, and you'll be fine for years to come. Cheap factories are the icing on the Domination-victory-cake.