Can I enable a new mod like CQUI in a Saved game?

For some reason, CQUI was suddenly activated in my save game after I disabled it due to the version not working properly with the latest patch. I'm not sure how it happened, but I'm glad it did since I was missing it terribly.
 
The CQUI is already compatible with latest patch, and it can be turn on in the saved game by add some code in the mod.
 
I subscribed to CQUI a couple days ago. It works WELL in the game I had already started.

MANUAL installations of it that I had tried several months (and a couple versions) ago did NOT work for me.
 
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