Events especially. I prefer do not playing with them. Same for Ancient ruins (it damages Shoshone a bit, nothing major). Anyway my list with some comments: _ Difficult: Emperor. I can win easily on King so increased difficulty. I have a good 40% wins with Emperor and improving. _ Map. Planet Simulator or Pangea or Standard continents. Strategic balance on Resources. This is by FAR the settings that make or break the game: if you go with standard resources and discover 0 Iron or Horses you are royally screwed. Coal to some extent. While I can reroll the map until i find a good start luxuries wise I cannot see strategic (I did use Reseed to test a map script but then my starting choice is made without strategic revealed on regular playing). Planet Simulator let you a bit more space to expand (Standard map). Islands options are interesting. _ 8 Civ, 16 CS. Standard. _ Pace: Epic. _ Settings: No Events, No Ancient Ruins, Raging Barbarians (sometimes), Barbarians giving GG/GA (sometimes), Transparent Diplomacy. All Victory conditions allowed. _ no tech brokering, no research Agreement, everything else on default _ Mods. _ VP complete with EUI _ InfoAddict _ 3rd and 4th components (Pineappledan). Recently added. Nice twists and a lot more flavor for every Civ. A monumental effort balancing and graphic wise. _ Building and unit tweaks (Pineappledan). First to improve power plants in every way, second one i'm still undecided on skirmisher line. No matter how you put it seems very hard to justify the whole line but in very open mats. Fragile. _ Trade opportunities, UI enhancements (city and list) from Mod Repository. _ faster aircraft animations _ Enhanced Naval warfare What about you ? Edit: mods section and settings section expanded.