I played this through for fun, almost done. I ended up doing an axe rush, late because I had not intended to do so. But at two cities Isabella inexplicably had only one archer in each city (whipped a second one in Madrid of course) so I faced a total of...three archers.
After that I expanded to 12 cities, all the way up to the rice/dyes/gems spot near Monty. Went aesthetics (marble) -> math -> lit -> music after writing. Built the GLighthouse, GLibrary, and National Epic in Madrid which made a top notch GP farm. Built the Parthenon, MoM, and Taj elsewhere. Got probably close to 2000 failgold from ToA, Shwadegon Paya, repeat-building the National Epic, and about 800 failgold alone from the Sistine Chapel.
First GS (a bit late, around 1AD due to the rush to block and fill my land) built an academy in the capital, where overlapping cities were helping it to develop cottages on all the FP and riverside grass tiles. Bulbed philosophy, 2xeducation, 1xliberalism, 1x printing press. Also produced 2 great merchants who were sent to the ToA.
I had no cities close to Monty early when he started plotting, he ended up at war for almost the entire game with Pacal. When I was close to lib Monty requested I declare on Pacal, which I did only to make sure Monty didnt make peace and start plotting on me before I was ready. All cities got barracks/stable/forge and prebuilt a good dozen horse archers for upgrade until Military Tradition was lib'ed and gunpowder was in. I self-teched nationalism before anybody else even had philosophy. Traded for alphabet, IW, monarchy as soon as someone got alpha (was late, but wasnt my priority). Later traded for machinery (after lib bulb), metal casting, engineering, feudalism (music and paper alone got me most of these).
The problem on this map is that even if you box Isabella in and claim lots of land, she will probably start to plot on you shortly after getting Iron Working (she has iron by her capital, you are her only direct neighbour, you are severely limiting her expansion, and she can plot against you at pleased). Thus it's best to get her out of the way early. Here the axe-semi-rush worked pathetically well, but if you want to move up to immortal the obvious strategy would be the Horse Archer rush.