For those who apply the patch and now suffer a CTD after the load screen, I had that problem and solved it.
The patch simply caused it to get by the init but go straight to crashing to the desktop. So I actually took my graphics card out of the machine, swapping it with an old crappy card. After trying that card (didn't meet requirements - black land, Cheshire cat issues) I swapped in the new card, refreshed everything, reinstalled the game, applied the patch, and it works fine. Note that I have an ATI Radeon 9550 256.
So I suggest actually removing your graphics card from your system - deinstall it in Hardware Manager and if you can get a hold of another card, run your computer with that. Then reinstall entirely. Solver suspects, and I concur, that a new detection of the card may solve this new problem.