I would say if you can run a large number of specialists, yes. I think Freedom & Civil Society is stronger than Rationalism & Secularism, but nothing prevents you from picking that up later, too, with your cheap artists generating culture for you. Plus, I find I sometimes like to pick up Theocracy so Rationalism is out of the question there.
Autocracy seems incredibly underwhelming considering that it locks you out of both an early expansion SP tree and a strong later tree. The only really useful bonus is the cheaper unit upkeep with the cheaper buying of units being good but not great (I find I don't usually have to buy so many units once I have an army set up that I can upgrade).
The -50% unhappiness from occupied cities can be gained through Planned Economy, the second policy in the order tree, which incidentally also halves unhappiness from your own number of cities as well (or does militarism decrease the unhappiness from pop as well?). Total War seems pretty useless, 33% for 20 turns is not enough of a bonus to even pick it in my opinion, unless you're struggling for your life. Becoming Russia is ok but probably not needed if you're warmongering anyways.
The #1 reason why taking Autocracy doesn't make a lot of sense at the moment is, however, that the AI is so weak at waging war that you simply don't need any bonuses for it. I would almost always take Order over it given the choice. In fact, I think Order should lock you out of Liberty and Freedom, too, so you have to descide to go the fascist or communist route or the democratic and libertarian route.