Well, I did it.
I went for Emperor difficulty and picked Babylon with the goal of using the strategy mentioned in this thread to win a science victory. My first roll I immediately had a very good start, with river, flood plains, hills, coastal but not too many water tiles, no mountains, tundra or desert, so I spent ten minutes planning out my city with a +7 Industrial Zone, a good Campus next to a reef that could build Great Library, and so on.
Then I settled in place, started exploring... and ran into Yerevan on turn 4.
So anyway, I completely retooled all the pins, going for religion instead. That meant I could pretty much ignore science, and for culture I needed Theology and later Divine Right. And some Governor titles. I got a rather late pantheon, and went for River Goddess, as I'm using the Better Pantheons mod in which it gives +2 housing, +2 food and +2 amenities. For my religion I took Reliquaries because I'd found a relic on turn 40 or something, as well as Mosques to make sure no AI could snatch it away. They never go Holy Orders so I wasn't worried about that one.
I then rushed for the Mahabodi Temple to use the two free apostles to evangelise my religion with Holy Orders (cheaper apostles) and the belief that gives faith from every city following your religion. Building that also unlocked Buttress, so that let me immediately continue with Hagia Sophia. I used Pingala as early-game governor to get more culture (city was growing nicely), with a switch to Moksha once I was ready to start spreading.
That actually took until the early Renaissance Era, and I somehow managed to string
three golden ages together with one city and no missionaries or apostles bought or used. I'm still not sure how, though I will say it included purchasing Great People of types I wasn't even earning points for as well as copious levying. I also got points for first to meet everyone and first to circumnavigate, which helped. And in the Ancient Era I somehow managed to be the first to discover a continent (on Pangaea!) and two natural wonders that were closer to an AI than to me.
Anyway, when everything was finally together - Yerevan, Hagia Sophia, Mosque, max promoted Moksha, Exodus of the Evangelists - I started purchasing apostles, a few with Debater but most with Proselytizer + Translator, and all with
seven charges. My first grievance penalty for converting cities was turn 149, I won the game in turn 176.
Also, in the meanwhile in my capital I just built wonders because I had nothing else to do. Ended the game with Colossus, Kilwa Kisiwani, Mausoleum at Halicarnassus and Mont St Michel. And I managed to boost Civil Engineering, lol. Here's what Babylon looked like on the turn of victory (behind the name are an Aquaduct and an Industrial Zone):
EDIT: Oh, yeah, and I had to refuse a city that flipped to me. You can see it on the right. Made me think about OCC domination with Eleanor where you're not allowed to build Settlers or declare war, but
are allowed to keep peacefully flipped cities. Then again, the regular peaceful domination was already enough of a chore for my liking lol.