How are you doing with your Factories? A lot of early crafting buildings go obsolete at Industrialization. If you have not replaced them with Workshop (Guilds) or Factory (Assembly Line) level buildings you could be missing resources you use to produce. Of those at risk are ... - Leather - Glasswares - Pottery - Beads - Toys - Lye - Soap - Baskets - Cloth - Furniture - Shoes - Hats - Rope - Flour - Paper - Books - Sails - Cheese - Dyes - Sausages - Tannin - Lacquerwares I suspect key resources like Furniture or Glasswares could be a problem if you have not replaced them with a Factory. Just watch out for Globalization tech since if not everything is converted over to Factories then you could loose access to resources you once had when all the Workshops go obsolete.