Save file is attached for reference. It's Owls of Minerva too, not Hermetic (that game was a total loss with 4 hostile civs within 6 tiles of my capital and I got stomped by turn 20)
This is a deity level game running the new Menelik II leader, and I am not sure when this started to happen (it was gone 1AM when I gave up) but suddenly spies no longer work for offensive missions - it is literally impossible to set any mission at all. None of the options work, and instead of the usual confirm options, all I get is the ability to move to a home city - nothing else works except counterspy.
It is possible this is to do with the new district, as I have not fully read up on the diplomatic quarter as yet but it seems broken to me.
There is also a nasty graphical bug when the did work - all the options spread out in a VERY w i d e line.
Has anyone else seen spy issues in this new version, as for me it is just plain broken