I really like the virtue trees. One of the improvements from Civ 5, IMO. From what I've played so far, they offer decent choice.
Prosperity will still be good if/when trade-routes get nerfed, of course.
Knowledge tree is the science tree *cough* Rationalism *cough*, and I am confident it can hold its own, since science is always king.
Might, being the "burn everything to the ground" tree, seems to me to be a huge step up from Honor/Autocracy. You still get the usual perks, but science from aliens, replacing settlements with your own upon destroying them, and experience towards affinity levels means the warmonger can get through the early game and keep up without needing to give up the on the warmonger tree itself.
Industry seems like it may be the odd one out, but I see it as the jack-of-all-trades tree. Military upgrades and CS bribes are no longer existent, so all that extra energy rolling in can be used to rush purchase buildings and units on the fly. Production boosts on top of it offers even more flexibility. Once the city queue is empty due to high energy/production, there is a ton of freedom. Need more science? Set cities on production ~> science. Want a growth boost? Set cities on production ~> food. Need quick military? Purchase and churn out units at blazing speeds.
On top of all this, there are extra rewards from mixing and matching.
Obviously there will be an "optimal" tree, but at a glance the virtues on the whole seem better balanced than Civ 5's policies.