Yes, we have no issues and can go to any era so far (up until Modern is how far we've gone in our games before ending the game due to one of us giving up). All we do is basically to clear cache before we start each session.I do not understand why it isn't the case for me
Do you go to late game (I mean Industrial era +) ?
It just works and provides a stable game including in Industrial Era with huge AI armies on the map. Perhaps there is an increased number of chat message pings, but even then that is all that really happens. There are no crash issues or weird transformations of units or teleports or anything abnormal at all.
Our client pings are 23ms for the closest client and 103ms for the farthest client (- two of us are located closely in California and the third player is in Calgary, Canada). So we are not in Europe.
Map type might perhaps have something to do with it. Maybe some map scripts might yield issues.
We prefer the "For VP maps", but we have also played Small Continents Plus with no issues.
We did notice once that starting on a Continents Plus (large or perhaps huge) generated a map with no resource tiles, so we quit that map.
Edit:
And when I say clear cache I mean deleting all of these files and subfolders, so that the cache folder becomes void. Then we run Civ5.
My DLC folder looks like this:
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