I usually play with - no tech brokering - no espionage - no random event - choose religion I think the first two should be quite common among civ players as tech trading between AIs are simply outrageous and the espionage system is nothing but a nuisance. Random events aren't so bad, they don't break or make the game for me, but it kind of screws up the recap at the end of the game. Do I really care to know a "vicious storm torn its way through a Mali city destroying some mines in the year 420 AD"? No, I don't give a damn, leave it out. I always enables choose religion because it is kind of weird always having Judaism and Hinduism as the dominant religion in every game.