My answer probably won't surprise anyone since they are top tier civs but my go-to civs that I can always win with are: 1) Germany The extra production from the hansa coupled with the ability to build more districts in your cities mean that I can more quickly get science and culture districts up in all my cities. I go wide and build hansas, campuses and theater districts in all my cities. I easily run away in science and culture. In my last game, I won a culture victory just a few turns from also winning a science victory. 2) Korea As the science civ, I easily run away in science in my games. I just go wide and spam the unique science district. My production lags behind but I can still get a science victory pretty easily or I leverage my science into a more advanced military and easily conquer my neighbors with units 2 eras more advanced. 3) Rome The legion is awesome! Once I get a few legions and archers I go on a classical era warmongering spree. I can easily conquer everybody on my continent and then with a huge empire, I settle down for a science or culture victory. What are your go-to civs that you can always win with?