Every time I play as the Gaians, Peacekeepers or Uni, I end up allied to the other two for the whole game, with Miriam and Yang as enemies (they fight each other too), with Santiago and Morgan as sometime enemies. In these sorts of games, I might try to get a diplomatic victory (sign pacts between previously mentioned factions, eradicate Yang and Miriam, beat Morgan and Santiago into submission or bribe them into pacts if possible).
When playing as my favourite faction (Spartans), I just can't please anyone, since the Peacekeepers are gone by the time I decide to run Democratic, nobody likes Planned economy, and nobody else likes Power. This sort of game is where I aim towards conquest. Believers and Morganites are much the same since Fundamentalist and Free Market aren't very popular SE choices amongst the factions either.
Also, being the top dog means that pleasing the others will be difficult. However, I'm in a position where I don't care how the others think of me, since I'll be able to bribe votes for governor (if I don't have enough votes under my own faction to win on its own), and transcendence, conquest or cornering the energy market won't be far off at this point.
Whether or not it matters that I can't please anyone depends on the faction I'm using and the victory I aim for. I figure its no use exhausting resources or using bad SE choice for the sake of pleasing them when all their base will eventually belong to me.