My favorite coffee shop. It's not very far away, has some very good pastries, a good tea selection, a patio with fire pits, and is also a brewery. Plus they have food trucks, a rotating selection in the evening and a Venezuelan one at lunch. And sometimes they host events; last week I went to a board game event they hosted.
If you mean on vacation... I tend to go somewhere different every time, variety is the spice of life as they say. Though if I had to pick a state, I'd probably choose West Virginia. It's nearby, tons of outdoor options and mountains, and it's not just one area that's interesting, pretty much any part of the state offers something to explore and a municipality to make your home base. Yes, in the area I've gone to the most, that municipality has fewer than 1000 residents, but there's a motel, a couple restaurants, a cafe, a bicycle shop, a couple other stores, and even an opera house that has a show about fifteen times a year, and what else do you really need? If you're really hankering for something different for dinner, there's a town of about 8000 people 50-60 minutes down the road that has a biergarten and my favorite Japanese restaurant, among other options. Or half an hour in the other direction, you can get some pretty decent barbecue.
Plus there are the famous country roads. Compared to the straight-as-an-arrow, surrounded-by-corn-or-soybeans, always-two-lanes-across back roads that cover most of Ohio, you feel much more alive when you're on a mountainous, curvy, one-and-a-third lane road with mediocre paving quality and a significant hazard to the side in West Virginia.