I switch between C4, E4, and D4 as white, with E4 being most common, and the English (C4) being the least common. Occasionally, I'll move a knight pawn a single space to finacheto the bishop, but I think playing C4 first is a better plan if you're going to do that. At least for my style.
As black, I'll usually play the Sicilian (C5) against the King Pawn opening, or pay E5. I'm not a big fan of the French as I find it to be a timid move, although maybe I just don't understand it. Not a big fan of Nf6 either, too easy to get the knight kicked around, again, for my playing style.
I havent really memorized openings past the first couple moves, and it wouldn't really be very worthwhile for me anyways since most of my opponents have even less knowledge of "Book moves" than me anyway. But I generally try to take control of the center. Usually I'll move either one or two pawns, then a knight, then a bishop, then castle Kingside. I usually try to play the rooks and queens last. Although not always.
Question though. My brother is quite good at "From the gut" chess, and he beats me at least half the time in spite of the fact that he throws the queen out as early as the second or third move. While I haven't really memorized long opening sequences, I have looked at them and have some vague familiarity with some of them. However, I have no idea how to effectively combat such unorthodox moves. Most of the time I'll try to harass the queen with pawns and knights, but usually I get tricked at some point and end up losing a rook or something equivalent, and then I often lose. What's the most effective way of dealing with over-opportunistic queens?