The Map
Heres where I was at 500AD. From the start I was intending to go for my usual spacerace. Maybe this time Ill beat conquistador63

The Start
I moved the warrior SW to reveal the cow and sent the settler 2S to the plains hill, initially thinking of settling there to get the extra hammer. When I got there and saw nothing but desert beyond, I re-thought. Next turn the warrior discovered the fish. Oooh, quandary. I regard fish as one of the best resources to have in your capital, but how to get it without losing other good tiles? I seriously thought about settling on top of the cow to get the fish and floodplains, but in the end I plumped for the woodland SW of the cow, losing the fish, to keep the rice. I very quickly came to regret not settling on the cow when it became apparent Id have to give the rice to my second city anyway: York went by the northern gold to umm, youll never guess yes thats right, to get the gold, but it thereafter gave me continual problems with lack of food.
Tough map this btw. If you moved the settler West, youd get the gold and have the option to pick up the fish later; if you didnt (and Im guessing most people wont have), you end up with a lot of trouble trying to get either resource. And overall not a lot of food or happy resources around.
The Disaster
Third city went down by the jungle-river. You can see it on the map. Yep thats the one, those city ruins just NW of Gao. The city was a city for about two turns before becoming city ruins, courtesy of some thoughtful barbarians.
It got worse.
My other warrior, returning from exploring the incense just too late to save the city spotted Mansas settler, about to become Gao almost the instant that my beloved city copped it. Mansa even had a skirmisher lurking around. Couldve killed the barbarians for me, but no, he had to sit around and watch my city. MY THIRD CITY go up in flames. Only two cities left.
The Recovery
After Id calmed down, I poprushed another settler to found Hastings by the copper/clams before Mansa grabbed
that site too. And I realized that, me now being completely boxed in with only three cities, there was no choice but to
destroy Mansa Musa. Skirmishers or no skirmishers. So I beelined construction, and declared in 225BC with around 6 catapults and a couple of axes/spears to defend them. Id never have done that if I hadnt been forced into it, what with Mansa being a good trading partner and Mansa having skirmishers. (Did I mention by the way that Mansa has
skirmishers? +50% city defence! I mean who needs longbows?). But it seems that by forcing me into that war, the barbs did me a favour. You see, it was
easy. Before the weight of my catapults, Mansa just seemed to curl up and well die, really. In what seemed no time at all I had six cities. Though I did rather regret not razing Gao, so I could refound where my razed third city was, as that wouldve made an amazing production location, especially now I knew it had iron. I left a Mansa a couple of weak cities to the south and made peace.
The Science
Since I didnt have stone or marble, I didnt bother with any fancy wonder tactics, I just cottaged as much as I could and with the science from that plus the proceeds from looting various Malinese cities, science seemed to be going well. I realized from the lack of AI contacts that me, Mansa, and Asoka were likely to be the only guys Id meet before caravels, and with Mansa weakened I wasnt going to get many trades from Asoka. So I decided to beeline for optics, ignoring my usual strategy of heading for civil service/literature.
And thats where I was in 500AD. 6 turns from optics very pleased with that because I cant remember ever getting optics before about 900AD before. Slight downer that I hadnt made any use of the philosophical trait no specialists at all so far, thanks to the lack of wonders or of any city sites with enough food for specialists (Id be interested to know how other people coped with that problem btw). But that just means when I do start using specialists, Ill get a lot of great people very quickly.
So far it looks like easy sailing to an early spacerace