You can practically play the entire DS game with the stylus that has no buttons, I don't see why it would be any different using the IR functionality of the wii-mote. Similarly, you can play the PC version just about entirely with a mouse and two buttons. Again, the IR wii-mote could replace that as well.
I'd go out on a limb and say that if there ever was a Wii version, it would probably be the best version as far as control layout is concerned. I bet they could make a pretty nice looking Wii version if they were so inclined. Sure it would be in 480p, but that wouldn't make it ugly by default.
For the record, I don't own a Wii.