I have long considered 43-civ to be vp's main event, so really I don't anticipate seeing much of this change. Sounds interesting though
On the topic of Iroquois, it's not a problem to stick with onondaga by any means, but if the intent is to represent the "other" Iroquois cultures, there are a number of other choices that come to mind, however for the sake of brevity I'll just pick one, on the basis that I have not seen it represented anywhere else, in any other mod etc: the Susquehannock were an Iroquoian culture that was a distinct polity from the 5/6 nations Iroquois represented in the game. They were eventually absorbed by the game's Iroquois, but largely due to interactions with European militias, they were once quite a prominent group and largely a victim of circumstance. Tracking down settlement names from pre-contact times is nigh impossible, but in early colonial era they became known for a settlement, "Conestoga". It never really achieved status as a great city of the world or anything like that, but neither did onondaga really, we're talking a "what if" alternate universe...