Can be air and water pollution boosted?
It should reduce all yelds by percentage - flat decrease hurts mainly small cities and largest cities are virtually unscratched.
It doesn't have to be 90% cut to final production/commerce/research/culture/espionage/money output.
Level 1 -> Level 10 cumulative effect for example would cut all yields by 50 - 75 percent, and all food surplus should be wasted + enough linear reduction, so cities shrink lets say every 10 turns on Marathon.
There is food waste parameter, that appears with excess produced food would be affected by pollution autobuildings.
Of course deadliest level 10 would be at 4000 - 5000 and you would have to try hard to reach this level.
High pollution levels would increase crime and lower education too.
If crime, both pollutions and disease are at absolute maximum and education is at absolute minimum unlocking all autobuildings, then city should have only 10% or even 5% of normal yields and would shrink every turn on Marathon.
But that state would require careful planning.... or using Nanotech/Transhuman tech level of weaponized espionage.
As for unhappiness and unhealthiness.... well idk lol
Ground Scrubber should be modified: there is no problem with water pollution at all past Industrial era. Industrial buildings should pollute water by producing sewage.
Now it cleans already clean water and pollutes highly polluted atmosphere.