Re: Sisiutil.
When I buy techs in Advance Start, I tend to find myself emphasizing mysticism and a religion tech so I am "guaranteed" a starting religion. I'll also usually go for masonry rather than bronzeworking: It's cheap, and lets you use the often-nearby stone or marble for a quick early wonder. It's also one step shy of Monotheism for Organized Religion, which really helps out getting your first couple buildings going in addition to your early wonder.
But yes (Re: Pitman), you do often end up with an advantage over the AI. This is why I tend to use advance start ONLY with enough points to found the capital.
Hm, is it possible to set all the players initially to human-controlled so we can optimize (even specialize) the AI starts, but then the computer plays the rest of the game?