Hi there,
Bought Civ5 on Mac App store. I have a 2011 Macbook Pro running Lion, with 2.2 Ghz Core i7 processor, 8 Gb DDR3 RAM, and AMD Radeon HD6750M 1024Mb Video card. I have all the video settings set to low or off (had to, as performance as the game went on continued to get worse).
Now...