...is just that, the whole world speaks English.
I have always hated London's position. It's only on the east coast, which means you have to build a useless port on the western end to get your settlers going 1 turn less. My solution was to build Southampton on one of the cows, which gets all the resources and puts cultural pressure on France, beside being a good seaport. This even leaves enough space for Newcastle to be relatively productive so you don't waste the Midlands.
Since England doesn't have Europe to start with, the secret is to get technology very quickly (I had assembly line in around 1750 and industrialism, fission by 1800, I think) and colonize America but NOT Australia (due to the land you don't want to get in order not to win domination). Everybody was at least 2 eras behind me.
Utrecht's importance can't be stressed enough. If you stay on the British Isles you won't have a chance to conquer France and then Germany. All those Dutch cities popping up in Africa and elsewhere will make your land area too large. In fact I had to reload multiple times near the end due to my land area exceeding that for domination (and I had to give away very good cities in New York, St. John, Caracas and Durban--see all those unhappy faces there about leaving the English civ?

). The tiny Arctic colony that the Russians built delayed my victory by 3 turns (I actually had it once ceded to me by the Russians but gave it away immediately to Spain).
A couple factoids:
1. How would you use those unwanted great engineers that spawn near the end due to all your industrial parks? You send them to a small colony in the middle of South America, use him to build an Olympic Park and liberate it to the Incans the next turn. See how many turns of golden age I have left?
2. Conquest trumps domination (see stats screen--I turned the culture up to 100% at the end).
3. Paratroopers are great after nuking a city.
4. Nukes do not need to hit a city to kill its defenders--it just kills everything in the 3x3 box. Good thing to know when your troops are right next to a city, or if you want to kill two cities next to each other (e.g. Beijing and Qufu).