Neither save really hurt my eyes as badly as I would have expected 
The space loss to Zara I can't really comment about too well - my games are usually over before 1800 (higher levels are faster) and some of my concerns might be due to the desperate situation.
For example, you have neither Representation for better specialists nor cottage-friendly civics and it shows in your economic output.
One thing that strikes me is that you have very little infrastructure in several cities, despite generous hammers.
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The 1320AD one also has me puzzled about your civics - this time you have Representation but you hardly run specialists. Serfdom provides too little be worth giving up Slavery (or possibly Caste System) - if your workers aren't doing their job in time simply build more.
Your underdeveloped cities are busy building defenders instead of infrastructure that will make them profitable quickly; for the garrisons you should have a dedicated military production powerhouse.
To help withe the infrastructure, I would also suggest Organised Religion.
You are working too many bad tiles... when better ones are available. Forests and plains farms are dubious, unimproved grassland and tundra forest is inexcusable. You pay maintenance for every city and every citizen... if you don't put them to use you are paying for nothing.

The space loss to Zara I can't really comment about too well - my games are usually over before 1800 (higher levels are faster) and some of my concerns might be due to the desperate situation.
For example, you have neither Representation for better specialists nor cottage-friendly civics and it shows in your economic output.
One thing that strikes me is that you have very little infrastructure in several cities, despite generous hammers.
***
The 1320AD one also has me puzzled about your civics - this time you have Representation but you hardly run specialists. Serfdom provides too little be worth giving up Slavery (or possibly Caste System) - if your workers aren't doing their job in time simply build more.
Your underdeveloped cities are busy building defenders instead of infrastructure that will make them profitable quickly; for the garrisons you should have a dedicated military production powerhouse.
To help withe the infrastructure, I would also suggest Organised Religion.
You are working too many bad tiles... when better ones are available. Forests and plains farms are dubious, unimproved grassland and tundra forest is inexcusable. You pay maintenance for every city and every citizen... if you don't put them to use you are paying for nothing.