I had no problems running the game out of the box, and my computer is below spec. I use the Harkonnen patch to clean up some memory problems in the end game, but nothing else.
As for polls, this poll is only 2 hours old, give it some time. And normally the only people who take the time to say anything, are the people having problems. If you aren't having a problem, you just continue playing, sometimes you may say something, but not often.