First Strike
First strike round(s) are special. The number of them is determined by looking at the number of first strike rounds of the attacker and the defender. Whichever number is greater gets the difference of values in first strike opportunities. For x-y first strikes (possible first strikes), the math is still unproven, but it looks like a 50% likelihood of getting a first strike each "round" possible.
A first strike round is like any other round, except that the first striker is the only one who can do damage. For example, if the attacker has two first strikes and the defender zero, the first two rounds have two possibilities – the attacker wins so the defender loses damage or the defender “wins” and nobody gets hurt. The odds in this round are just like any other. The first striker is just immune to damage.