Veras
Prince
I agree with defiler and the OP, but here are some thoughts:
I may be wrong, but I believe Vitória was named so after the Portuguese won a battle against the indigenous of Espírito Santo, so it'd mean "Victory", not "Victoria".
This only proves, however, that cities named after given names aren't common (or famous) in Brazil (maybe in other countries as well), and thus they sound weird to Portuguese speakers. Even Dom Pedro II or Getúlio Vargas didn't inspire city names such as "Pedro" or "Getúlio". "Petrópolis", "Pedro II" or "Pedro de Alcântara" is another history, though.
So even if there was an important Manuel in Civ BE lore, I don't think the colonists would name a city simply after his given name. It'd be something like "Brigadeiro Manuel" or "Manuel Ferreira" or even "Manuelópolis".
This. It wouldn't be a problem to call a city "Manoel" if there were some indicative of who he might have been. Considering that the Firaxis team is naming planets after themselves, maybe there is some Manoel in their team?
Well, what about the other city names we've seem in the Affinities livestream? They were Santo Adrião, Dourado, Fiel and Boa Esperança.
Santo Adrião could be named either after some Portuguese villages, which is unikely, or after Saint Adrian of Nicomedia. This name is ok for a city, but is odd for some reasons. First, here in Brazil we use Adriano instead of Adrião. Second, this isn't exaclty a Saint with much appeal around here. So much so that I never heard of him. He's more famous in Northern Europe and in Orthodox countries. But his significance is understandable: Saint Adrian is a military Saint, protector against plagues, and patron of the older soldiers and weapon's traders. But again, Saint George is far more known and revered here in Brazil.
Dourado is also ok for a city, althougt the name alone seems kind of random. It means only "golden".
Same with Fiel (Loyal, Faithful. Can also means Believer, the opposite of Infidel). I could see a city named this way, but alone it carries little meaning.
Boa Esperança (Good Hope) is a great name for pioneering and explorer civilizations. Portugal named the Southern part of Africa as "Cape of Good Hope", after all.