I've had problems *playing* Civ3/Civ4 on my system, but it's hardware-related. I think my mobo is preparing to die.

I had no real problems *installing* though. (Although I do seem to recall that sometimes a window would pop up about the CD having an autorun function, and would I like to run that. This popup would be hidden under other windows, and Iif I missed it to close, things wouldn't go right.)