I usually play on Tiny, 5 players, lately on archipelago with sneaky continents, low sea level, Flavourmod 2, no technology brokering. I'm not a fan of large empires, on this setting each of the 5 players get to build 5-7 cities before they run out of productive land. It makes me more focused, though I still haven't finished many games. I used to play on as large maps as possible, but recently changed my mind completely.