Trev
Prince
In general building cities in dead zones is not worthwhile until all better sites have been built on, and development of existing cities would be a greater benefit in that case, so roads and maybe some irrigation before the establishment of cities in dead regions should be considered. However these days I build triremes much earlier than I did in the past and trasport settlers to coastal sites where they can access whales preferably, or fishes and establish these cities with harbours before I build in dead zones, the payback in trade is much quicker doing this.