I learnt about checkerboard cities back in my Indian game when I built most of my cities on the Indian Peninsula eventually had massive food shortages because none of my cities had the city squares to support its size... so in this game I have my cities spread WAY out. (I have all of Asia and Africa, and the Romans, my only other neighbor, I have contained at the Turkish Isthmus between the black and Aegean Sea and in the Ukraine so this is possible)
My general reasoning is to build 20 cities by AD1 and then spend the next 2000 years growing them into size 20-36 super cities with one purposely left at about size 12 that can provide the food to support all my engineers. (Who will be busy building railnets and farmland/cleaning up pollution)
Starting in the early 1900's (or whenever I have my spaceship done and am just aiming to max out my score), whenever I happen to have 30,000 or so gold to waste I'll find a good undeveloped resource "area", send it 10 engineers to totally irrigate and railnet the whole thing, and then have one build a city there. Then, I'll rush build all of the improvements and turn it into a modern city. Once I have about 3 of these I jack up my Lux rate to 90% and turn them into full size ~30 cities.
However, I have never used the ICS. It looks too boring and repetitive to integrate as a real style...