I often got Computer around T140. I think
Science is extremely important in every type of VC.
By the way, I never build Commercial Hub. I'm very negative towards this useless district.
Without Commercial Hubs, how do you typically generate gold for buildings, units or great people?
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As for the science/culture balance, just as Computers is a turning point for tourism, so is the Enlightenment for science and gold generation (the policy cards basically turn libraries into universities and markets into better banks). Even without too many theater squares, it's worth at least investing into early monuments, and picking a culture-boosting pantheon like Open Sky.
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