i had an awesome start once, but really weird.
had a 2pigs, 3 corn, iron under the city (it was on a hill), 1 copper in the North-Northwest corner of the Fat Cross, 1 wine, 1 gold, 1 stone, and 1 marble. i had swords rampaging all of my neighbors and wonders cranking out every thirty seconds. had a river cut through the entire thing and branch off into two at the hill my city was on. to the east of the river were most of the production resources, and the west, the food, which was on a desert, so naturally it had floodplains. however, the next city i placed had absolutely nothing.