I've noticed that in my game some of my cities have much higher demands for science/culture/etc than others. I imagine some of this is because of the buildings that "reduce boredom/poverty/etc" but this seems to be the case even when cities have the same buildings. Is there random variance in citizen demands? If so it might affect national wonder and GPI placement (e.g I might put Oxford and an Academy in the city that randomly decided it wants high literacy).