I just installed the patch this evening. Everything went fairly smooth until I started playing one of my saved games. After playing several turns, I went to save the game, but it wouldn't let me change the name of the save file; it was as if my keyboard wasn't working (but that wasn't the problem, I later discovered). So I quit the game and restart, and reload the game... and the problem reappears when I try to save again. So I quit again, restart my computer, reload Civ4, reload the game, and that seemed to fix the problem.
After about 6-8 turns of play, the problem resurfaces, but in another place. I tried renaming one of my new units (I am playing the Romans and giving them latin-esque names) but when the dialog comes up to enter the new name, I can't type anything into it. I try several times, but it doesn't work. And again, if I save my game, I can't rename the filename.
But then by accident I discovered what was going on. I tried to rename a unit again... and that's when I noticed that each key I typed was performing a hotkey action! This was happening even though I had clicked into the text box and got a blinking cursor... it was still transferring all keypresses to the game screen as hotkeys instead.
This isn't a total gamebreaker, but it is extremely annoying (it kinda ruins the flavor of my current game; I'll probably shelve it until this is fixed and play a new game)... the more annoying part is not being able to rename my save games (which I like to do sometimes to annotate particular events). However, I imagine this could become a gamebreaker if I tried to play in multiplayer mode and couldn't type any text in the chat dialogs...
Has anyone else had this kind of thing happen?
Oh yeah, it also set the date back in my game by about 20 years for some strange reason...
