Of course, if you had ever played games of - say, Axis & Allies (the board game) with your friends, you would be quite used to those '12 hours of wasted life'.
The underlying theme, there, is friends. To me, I can not see joining a server, ala Quake, and playing as such - if that is how it is usually done. I, at least, would like to know the people I am playing against. The drop out factor would be a total drag in a public server format, as well as the fact that not everyone could complete a game in one sitting -- RealLife (tm), and all that.
In my case, I have only converted one of my friends to Civ III. Not much prospect, knowing this person, of getting many games in - heh.
In a turn based multi-player game, you would need to be comfortable with those you are playing against - in my opinion.
So my question, I guess, is whether or not the community is broad enough to support the more part-time players out there. Will you be able to just pick up where you left off the next day, or two days later?
I am a bit skeptical about that.
Now, if they got it so specific eras, or scenerios were available to play online, there would not be this fear of people quitting mid-game or never being able to complete a game, period.
It would certainly help out in my case.