From memory, civ5 patches rarely caused impact to most mods in comparison to other moddable games like EU4 or Minecraft which always seem to break mods with every patch. IIRC, the biggest impact to civ5 patching tended to be mods that used custom DLLs (C++ modding).
But in saying that, the CFC community seems to have a good ability to quickly get things working again in little time. Of course, it does help to have a few resident gurus on the forum who are quick to highlight changes and mentor fellow modders.