Originally posted by Scyphax
Never take the first offer.
Lets say I want Invention, I will ask the AI civ what they want for it.
They might reply - Printing Press and Education
Then I ask them what they will give for Printing Press and Education.
Often they add sometiming to the pot like ivory, gold and/or a map.
The best time to trade a tech is just before you (or anyone else) completes the associated wonder.
If I am one turn away from completing Bachs Cathederal I will sell (or give it away just for the good reputation)
Sell to the richest Civs first and finally give to the poorest.
Be careful when selling to a Scientific civ, if it is the last tech of the age they will get the tech you are selling plus a freebee.
If you are a Scientific civ it is often worth paying extra for a tech that is the last of an age as you will get that tech, plus your freee tech earlier.