Any way to mod game in process

[chipbuffalo]

With Civ 5, I was able to make little tweaks during game play with a feature that I don't remember the name of.

I am not able to find that feature with 6 and wondering if there is something out there that will allow me to do that?

 

[Tiramisu]

What exactly do you mean? XML tables are read only. The only thing you can use during the game are Lua scripts.

 

[Infixo]

You can activate any mod for a game in progress (load save) as long as it has the flag AffectSaveFiles set to false (0) and it doesnt change DB much. Sometimes the game wont allow you to do so (you will go back to loading screen).
The effects you get is a different topic.