At high difficulties (immortal, deity) it seems to be 250-300 turns before the human or an AI achieves one of the victory conditions.
I'm playing monarch and usually win or lose around turn 350-400.
If you're asking about hours, I happened to check through my games yesterday and the most recent ones take about 6-8 hours to win a Culture/Space win (Prince Difficulty). Not sure, but this is probably multiple hours faster than I used to play and skill is probably a huge factor in that.
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