Well, since we seem
The GUI. It may sound like such a trivial detail, but I think there are many, many ways the interface could be improved and streamlined. For one thing, I find the whole concept of the city screen outdated. With current horsepower it should be trivial to implement menus that smoothly pop up when you mouse over or at least select a city. With translucencies it can be made very pretty.
Oh dear me, no. I want Civ 5 to have something more like a Civ 3 or even Civ 2 city screen/main map balance; less junk on the main map, more information city-by-city.
I mean, I can mouse over a city and already get alot of info in Civ4. GP points, food growth, production, most of it I can see.
Some of us find this gets in the way.
EDIT: Oh, while I'm at it, it'd be nice if displayed information was more context sensitive. Like, currently we can toggle tile value, grid and resource markers on and off at will, but why not make it so that they automatically come on when we'd want them, like selecting a city or worker? Tile vals already show up when selecting a Settler, why stop there?
Because having the computer guess what I want when I want it would make the game unplayable, because it will never get it right enough of the time; it would be like Microsoft Word thinking it knows how to spell better than I do.