Gen.Rommel
Warlord
I have no issues using nukes on anyone, since most of the time, the civs that get nuked in my games are the ones that are really pissing me off. However, the economic downside for you is the unbelievable global warming. In about a hundred years, pretty much every patch of land is turned into desert, reducing all your cities to ghost towns, with only a few hammers of production. Thats the only reason i dont want to use nukes anymore. If only the stupid AI would clean up his fallout, then i wouldnt be losing production.