i won´t be able to play this out, but i liked the setup a lot and probably will finish the game when i find the time.
what i would have liked to do is a history model an enemy for each era: like, first America would fight the Indians, including the Iros. Then the English, after them the Spanish. France would be a friend most of the time. Win per Space against Russia and keep China fund your budget deficit
my starting moves were:
worker east to cow, scout north sees game so 4turner is possible settle in place.
start full speed on Alpha... either i have to self research it if all those tribes with Alpha are on another continent or i can get a discount on trading it.
build scout-warrior-granary
a combo factory 5-7 doesn´t work by one shield if i count correctly, so i plan 4-6.
meet Cherokee in 3700 and Sioux in 3650. see that the latter have ivory. Apache in 3600, they probably popped CB from a hut.
meet France in 3450. cannot make a trade for Alphabet, they already know my techs. after their contact with the Cherokee i can cut this: BW for Masonry+7g.
in 3150 my whole economy could buy Alpha, but it´s only 15 turns away and i abstain for now.
the following turn the French even offer a worker... :-(
build granary in 3050. meet Iros in 3000 and trade for Alphabet+CB+some coins. Writing in 40.
i fell quite boxed in, but since the next tribes cannot build any more settlers, i feel comfortable about REXing with a SF (for now).
see first barb in 2900 :uh:
about research i feel with Lanzelot, i too thought my Philo date of 1325bc for the slingshot was pretty good, but it was still too late for a free tech
i played cat and mouse with the minor tribes and think i played that game quite ok. their units got used up against each other, against the French and the Iros and i took their powerful cities with very useful wonders. jumping to that scene, that´s the way it went:
when the time comes to declare on Sioux, the last and very mighty minor tribe left, i lose one 1st ring city immediately, but take Cuzco with The Colossus the next turn. in the following turns i lose half of my core

and take it back town by town. with Tiwanaku (the horse town) i take the 2nd town i wanted to gain in this war. all but 1 of my own towns are back in my hands. time to think peace and try to get this in the negotiations... and to kill some more units to get the price down and yes, a leader in 510bc! peace is made.
470bc FP in Cuzco built
in 130ad the horse town deposes to the Sioux... war is ahead again. so when their troops are past the choke, i shut it so they won´t come back

get Lizzy into war with the mighty Iros and then ask remove or declare... she declares, i kill her single landed spear and get a leader. build longbow army

have never had one before and will have to defend it well.
then 290ad i start my last war against the Sioux. take horse town back in the first turn, with all improvements still in it! only minor counter-attacks on IT. next turn i manage to take Copan, one city left. in 330ad, finally, i take Chichen Itza with SoZ and Oracle, and eventually i´ve got iron! plus a 3rd lux. things definitely look brighter now.
when i will continue this, i´ll have to prepare for war against the runaway Iros.