- A lot more customization, you can change map sizes, number of opponents, different types of maps, game length... also in general the games take longer
- The AI is not extremely aggressive, (unless you select a specific setting) you can form friendships and alliances (often around religion), also each AI leader has a specific personality, it isn't always "you vs. AI" like it is in rev
- Fighting is different... not entirely sure how it works in revolution but there are no armies, you just make large stacks of mixed units, you can see your combat odds of each fight before attacking cities
- Leader traits tend to be more subtle, no extremes, also unique units and buildings (are those in rev?), also most world wonders are toned down (and upgrading units can be done anytime but costs money, it isn't tied to a wonder)
- government civics are completely different, also no anti-war governments that prevent fighting