I think, over the internet it is hopeless. A game takes too long, and when you safe it for later continuation, you'll never get the same set of people together again...
I played a lot of PBEM here on this forum, and that was quite nice (if you are willing to accept, that a game lasts for 2-3 years... Kind of like Postal Chess...), but the PBEM community is quite small by now. I think there are just 1-2 active games left at the moment.
Finding 2-3 friends at home and playing a LAN game is about the only chance, I think.