I have tried twice (with Incas in Warlords). One false start, where I quicky learned you really need to choose your opponents, and choose them without the protective trait, if you want to go for the early Quecha rush.
My second try, I came frustratingly close to winning. I sort of lucked out finding a starting location for my capital after a couple turns of exploring -- a plains hill with marble, which produces three shields when you place your capital on it, with another plains hill with trees within the City boundaries. So I was producing 6 shields a turn and cranking Quechas out (my capital did not grow past three the whole game). My capital was close to three other civ capitals, all eliminated with ease (since they were all close, I kept those cities, so I had four total, one which ended up yielding a source of iron). After taking them out, I took the time to build Stonehenge in my capital, which helped all my cities' culture grow (and which was my sole use of Huyana's industrial trait).
The others three civs were much farther away. For two of them, I was able to prevent them from getting horses or metals, and took them out with a fair amount of effort. (By this point, I was using chariots and then horse archers, as well as swordsmen and axeman, together with the ever useful Quechas.) I raised all but one of those cities (keeping one to have a remote "home base" to work from -- no units supply costs for units stationed in the city.)
Bismark was the last civ, and I came close to taking him out. However, my momentum faltered, and my unit costs, together with civil unrest/war wariness back home (probably exacerbated by my excessive use of slavery to rush units and keep population down) brought my economy to a screeching halt and fatally limited the number of units I could support. Also, as it turns out, Bismark had a remote city on a separate island I could not reach, where he was apparently getting a source of iron I could not take out. He had caravels, which prevented me from getting galleys/triremes there to even explore (and it was sooo far away it would take forever to reach by galley anyway).
Finally, I learned that I really need to stop being stubborn and turn off those !@#$ barbarians for this type of game. With the vast expanses of un-settled open terrain left open by my razing of cities, they really started to become much more than a nuisance, particularly at the end when they came at me with longbowmen and I did not have Fuedalism (if I had that, I think I might have beaten Bismark down enough to convince him to become my vassal, so I tried to reach it, but could not in time). If not for the units and time I lost to barbarians, I think I might well have won this game.
(By comparison, the barbarians proved a benefit in the G-Major/space race game, as they helpfully built a number of useful cities with some improvements for me to conquer in the "americas" on the terra map, so I did not have to build and send over as many settlers to take over that continent and was able to start out with cities which were already partially developed.)
At the end, my efforts did not prevent Bismark from shooting far far ahead of the research curve -- my horse archers (with a shock promotion) and swordsmen (and catapults), in sufficient volume, were barely able to take out his macemen and longbowmen and even his pikemen, but I finally gave up when I saw those musketmen. Arggh!
I will try again at some point soon, but I really need to do other things with my time.