Bibor
Doomsday Machine
By the time you have both a university and an observatory you're probably not going to have that many renaissance techs left. There's also the fairly strong argument that a tech now is better than a tech in 100 turns time, and another 150-200 turns after that, especially if you're slingshotting deep.
That's because you make the two most common mistakes that people do:
a) that there's an infinite number of turns
b) that there's an infinite number of available scientists
Lets say you need to research an average of 60 techs per game (depending on your victory conditions, of course). Also lets say the game lasts, on average, for 350 turns.
How many great scientists can you produce during the course of that game? Lets say 6.
Lets say you get your 1st Academy in the Classical era and you build a national college there:
5



You get the 2nd Academy at time you get your University in the Medieval era:
10



You get the next 3rd Academy early renaissance and you build an Observatory there:
15



You get the 4th Academy at late renaissance and you build a Public school there:
20



You add a 5th Academy in the industrial era:
25



You add your final 6th Academy in the modern era as well as a research lab:
30



***
Total number of beakers needed to research 60 techs: 53225

Average number of possible beaker gains from bulbing: 7860

Real effect of bulbing: 14% of total science needed (excluding the last 14 techs).
If all research would be equal during those 350 turns, the research pace would need to be 152



How about that.
The only thing you need to do is to build your science city adjacent to a mountain and with lots of production.
EDIT: High empire-wide research lowers the effects of both bulbing and Academies.